A woman collapses on Black Jack's flight to Tokyo and requires immediate emergency treatment. The airplane is redirected to South Korea, but it is a trick, and Jack is abducted and taken to the neighboring country of Anryon. Jack is pressured into treating their leader, General Che Hyoku, who is suffering from a glioma, however he is allergic to common anestheitics. Jack is also caught in the midst of a violent political struggle for power between the general’s militant son Tebyon and a revolutionary group led by his other son Jongi.